Study Objectives To explore the cardiovascular effects of nightlong repetitive arousals(RA) induced by auditory stimuli.Design Each subject participated in two consecutive sleep studies with the first
目的 探讨即时及长期持续正压通气治疗(continuous positive airway pressure,CPAP)对于阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)患者血管内皮功能及自主神经调制的影响方法 共有23例呼吸暂停/低通气指数(apnea/hypopnea index,AHI)≥15次/h的OSAHS
Aim Obstructive sleep apnea hypopnea syndrome (OSAHS) is an independent risk factor for development of hypertension.Epidemiological surveys have found that risk of cardiovascular diseases increased in
PURPOSE Although there is a high co-occurrence of insomnia and obstructive sleep apnea(OSA), the administration of sedative hypnotics in patients with OSA is still inconsistent.The aim is to study the
BACKGROUND Growing evidence from population and clinic based studies showed that obstructive sleep apnea (OSA) and its characterizing chronic intermittent hypoxia (IH) were independently associated wi
目的 观察阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)患者认知功能障碍与事件相关电位(Event-related Potentials,ERP)的关系,研究OSAHS患者认知功能障碍的客观评价.方法 以MoCA量表对多导睡眠图(polysomnogram,PSG)确诊的36例中重度OSAHS患者及17例正常对照进行认知功
目的 观察慢性间歇性低氧(CIH)大鼠肾组织形态学及其氧化应激相关指标变化,探讨CIH的肾损害机制。方法 将40只SD大鼠随机分为4组,CIH组2周和4周组(2IH和4IH),对照组2周和4周组(2C和4C),每组10只,采用化学比色法检测血清SOD活力,肾脏称重计算肾脏、肾体比,HE染色、PAS染色和Masson染色法观察肾组织病理结构变化,,RT-PCR法检测肾组织HIF-1α、Cu/ZnSO
目的 探讨不同发病年龄的老年阻塞性睡眠呼吸暂停低通气综合征患者临床特征的差异，为个体化干预老年OSAHS提供参考依据。方法 研究对象为2009年6月至2014年2月在广西睡眠呼吸疾病诊疗中心行多导睡眠图检查，就诊年龄≥60岁确诊OSAHS的患者。剔除既往行nCPAP治疗者、无法明确发病年龄者(如独自居住者)、脑梗塞、脑出血、心功能衰竭、呼吸衰竭者。患者睡眠习惯性打鼾，此后发现患者鼾声不规则或呼吸中
目的 探讨打鼾者颈围、体重指数、Epworth嗜睡评分(ESS)三参数与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的相关性,评价三参数积分筛查打鼾者OSAHS的价值.方法 2009年5月至2014年6月,广西四家医院2955例30≤年龄＜60岁打鼾者行多导睡眠图(PSG)、人体测量参数及ESS评分.比较OSAHS和非OSAHS差异.对OSAHS危险因素进行相关分析.最优离散化选最佳颈围、BMI及
OBJECTIVES To verify the effects of oral appliance (OA) on upper airway morphology under intraluminal pressure, identify specific sites of upper airway collapsibility that can be reversed by OAs,and d