An Empirical Bayes Method for Genotyping and SNP Detection Using Multi-sample Next-generation Sequen

来源 :上海交通大学 | 被引量 : 0次 | 上传用户：jayleardutt

【摘要】

：

The development of next generation sequencing technology provides an efficient and powerful approach to rare variant detection.To identify genetic variations,the essential question is how to quantity

【作者】

：

Gongyi Huang Shaoli Wang Xueqin Wang Na You

【机构】

：

School of Mathematics,Sun Yat-sen University,Guangzhou,510275,China

【出处】

：

上海交通大学

【发表日期】

：

2016年4期

【关键词】

：

Next generation sequencing Single nucleotide polymorphism (SNP) Rare variant gen

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　　The development of next generation sequencing technology provides an efficient and powerful approach to rare variant detection.To identify genetic variations,the essential question is how to quantity the sequencing error rate in the data.

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An Empirical Bayes Method for Genotyping and SNP Detection Using Multi-sample Next-generation Sequen

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