VSMC-derived XBP1u Deficiency Contributes to Abdominal Aortic Aneurysm via Regulating VSMC Phenotypi

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:z4360877
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  Rationale: Vascular smooth muscle cell(VSMC)phenotypic switching proceeds the pathogenesis of abdominal aortic aneurysm(AAA).X-box binding protein 1(XBP1),a basic-region leucine zipper(bZIP)transcription factor,involves spliced(XBP1s)and unspliced(XBP1u)isoforms.
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