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5. Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants

Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants

来源 :中国药理学会北美分会药理学学术大会 | 被引量 : 0次 | 上传用户：wszlzsjava

【摘 要】

：

The recent Middle East respiratory syndrome coronavirus(MERS-CoV),Ebola and Zika virus outbreaks exemplify the continued threat of(re-)emerging viruses to human health,and our inability to rapidly dev

【作 者】

：

Wei ZHANG Ben A BAILEY-ELKIN Robert CM KNAAP Baldeep KHARE Tim J DALE-BOUT Garrett G JOHNSON Puck B van KASTEREN Nigel J McLEISH Jun GU Wenguang HE Marjolein KIKKERT Brian L MARK Sachdev S SIDHU 

【机 构】

：

Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Resea

【出 处】

：

中国药理学会北美分会药理学学术大会

【发表日期】

：

2017年10期

【关键词】

：

MERS CCHFV deubiquitinases phage display ubiquitin variants protein engineering 

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　　The recent Middle East respiratory syndrome coronavirus(MERS-CoV),Ebola and Zika virus outbreaks exemplify the continued threat of(re-)emerging viruses to human health,and our inability to rapidly develop effective therapeutic countermeasures.

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