论文部分内容阅读
Lead is a risk to infants during early development, thus it is important to evaluate the environment of pregnant mothers and infants by multi-linear regression analysis.This prospective study assessed the effect of foremilk exposed to low levels of lead on the early development of 128 infants using neonates whose foremilk lead levels were determined by atomic absorption spectrometer.Early infant development was evaluated using the Bayley Scales at 3 months of age.Infants were classified into two exposure groups of >≥ 0.24 μM (high lead group) and < 0.24 μM (low lead group).The mental development index (MDI) and psychomotor development index (PDI) were inversely related with foremilk lead levels.Infants with foremilk lead levels ≥> 0.24 μM tended to have lower MDI and PDI compared with those whose foremilk lead levels were < 0.24 μM.There was a significant difference of MDI and PDI between high and low foremilk lead groups.Multi-linear regression analysis revealed that the contribution of maternal age calcium supplementation to diet nutrient composition during pregnancy as well as severe environmental pollution in their residential area were still statistically significant after adjusting for other confounding factors.The calcium supply during pregnancy was a protective factor for foremilk lead exposure.In conclusion, foremilk lead levels > 0.24 μM have harmful effects on the development of infants at 3 months of age.