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The fire has brought great harm to human, so it is of vital significance to establish a scientific method of structural fire resistance design toavoid personnel casualties and economic loss in the destroy or collapse of the structure in fire.The mechanical properties of materials deteriorate at the high temperature of the fire, and the structure can be damaged easily, so the damage cumulative impact must be considered in the structural resistance capability to fire.Damage mechanics is a powerful tool in the study of structural damage and destroy.In the paper, the damage mechanics is introduced into the calculation of resistance capability to fire of concrete structure, and the thermal-damage analysis of concrete member is achieved through the second development on ANSYS platform by using the residual strength thermal-damage model at high temperature.