G-quadruplex/hemin DNAzymes have been the focus of an intense interest recently owing to their quite unique enzyme-mimicking properties,but limited by its much lower catalytic activity than that of pr
Chiral environment widely consist in the life system,as has been the case for the basic components in the body of an organism,like sugar,fat,protein,nucleic acid and so on.
Dendrimer-like DNA nanostructures have attractive properties such as mechanical stability,highly branched nanostructure,customized sizes,and biocompatibility.
We herein demonstrate that DNA origami can work as a multifunctional platform integrating chemotherapeutic drug(doxorubicin),gold nanorods and tumour-specific aptamer MUC-1,to realize the effective ci
Malignant tumor is one of the most serious diseases that affect human health.As patients with long-term chemotherapy,multidrug resistance of tumor is the most prominent problem.
Due to the specific properties of fluorine atom,such as small size,high electronegativity,carbon-fluorine bone strength and sensitivity of 19F NMR,the introduction of fluorine atom(s)into biomolecules
m6A is the most prevalent internal modification in eukaryotic mRNA and preferentially occurs at the consensus sequence [G/A/U][G>A]m6AC[U>A>C] with a non-stoichiometric ratio.Although it was first fou