【摘 要】
:
Objective Ischemia heart disease (IHD) is one of the leading causes of human death.Mitochondrion as an important organelle play important role in IHD.Previous studies revealed that Rg1 the major pharm
【机 构】
:
Macau University of Science and Technology, Macau
【出 处】
:
第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会
论文部分内容阅读
Objective Ischemia heart disease (IHD) is one of the leading causes of human death.Mitochondrion as an important organelle play important role in IHD.Previous studies revealed that Rg1 the major pharmacologically active ingredients of ginseng can protect cardiomyocytes against the hypoxia/reoxygenation (H/R) injury by enhancing myocardial angiogenesis and improving myocardial function.However, the mechanisms of Rg1s protective effects on mitochondrion remain unclear.The current study aims to investigate the mitochondrial protein change associated with the Rg1 in the H9c2 cell H/R model by proteomic techniques.
其他文献
Sterol regulatory element-binding proteins (SREBPs) are major transcription factors regulating the expression of genes involved in biosynthesis of cholesterol, fatty acid and triglyceride.We investiga
During the last years three different masters-projects have been pursued (partly in collaboration with the Dept.of Information Technology at Uppsala University, and the Chemical Computing Group at Ast
Excessive activation of microglia that detrimental to neuronal survival is closely associated with many neurodegenerative diseases.Astragaloside Ⅳ (ASI) is a natural saponin molecule found within the
A Gram-positive, aerobic, non-motile and pale yellow coloured actinobacterial strain, designated SYP-B575T, was isolated from rhizosphere soil of Panax notoginseng.The optimal growth of the strain occ
Two new compounds, elucidated as Iobatoside L (1), lobatoside M (2), and nine known cyclic bisdesmosides (3-11), as well as 25 other known compounds (12-36), were isolated from the Actinostemma lobatu
Gynostemma pentaphyllum (Thunb.) Makino (Cucurbitaceae), refers to Jiao Gu-lan in China, was widely cultivated in the south of China and extensively used for a long history in folk medicines as a reme
High-altitude polycythemia (HAPC), named "Plethora" in Tibetan medicine, is a chronic altitude-induced disease characterized by hyperplasia of red blood cells due to hypoxia and can seriously jeopardi
As a major source of Chinese medicine and the world traditional drugs, medicinal plants are facing challenge of resources scarcity and low content of bioactive compounds.Gene expression regulated by t
Plants belonging to Clerodendrum (family Verbenaceae) are well known for their pesticidal properties.C.bungei, a small shrub mainly grows in the central and western regions of China, has been historic
The process of drug discovery and development particularly that of natural products, has evolved markedly over the last 30 years into increasingly formulaic approaches.As a major class of natural prod