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Objective: To determine the association between visceral pleural invasion (VPI) and post-operative prognosis in early stage non-small cell lung cancer (NSCLC).Method: Between November 2007 and November 2011, 261 NSCLC patients (pathological stages Ⅰ or Ⅱ) underwent radical resection in the First Affiliated Hospital of Jilin University.The associations between VPI and survival rates of these patients were retrospectively analyzed.Result: The one-year overall survival (OS) of patients with or without VPI were similar (90.77% and 93.13%).