Calcineurin-NFAT signaling and neurotrophins control transformation of Myosin heavy chain isoforms i

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：clxzzx

【摘要】

：

【作者】

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Wenfeng Liu Gan Chen Fanling Li Changfa Tang Dazhong Yin

【机构】

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Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal Universi

【出处】

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中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

：

2014年3期

【关键词】

：

aerobic treadmill training the muscle fiber type neurotrophins Myosin heavy chai

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　　This study elucidated the role of CaN-NFAT signaling and neurotrophins on thetransformation of myosin heavy chain isoforms in the rat soleus muscle fiber following aerobicexercise training.To do so, we examined the content and distribution of myosin heavychain (MyHC) isoforms in the rat soleus muscle fiber, the activity of CaN and expression of NFATcl in these fibers, and changes in the expression of nerve growth factor (NGF), brainderivedneurotrophic factor (BDNF) and neutrophin-3 (NT-3) in the soleus and striatumfollowing high-and medium-intensity aerobic treadmill training.

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Calcineurin-NFAT signaling and neurotrophins control transformation of Myosin heavy chain isoforms i

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