Protein Quality Control Nanomachines in Action Revealed by Near-atomic Resolution Cryo-EM

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：w6832793xym

【摘要】

：

　　Cellular protein homeostasis is maintained by protein synthesis,correct protein folding and efficient proteolysis.Two ATP-consuming molecular machines help

【作者】

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Yao Cong

【机构】

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NationalCenterforProteinScienceShanghai,InstituteofBiochemistryandCellBiology,ChineseAcademyofScienc

【出处】

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中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

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2018年10期

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论文部分内容阅读

　　Cellular protein homeostasis is maintained by protein synthesis,correct protein folding and efficient proteolysis.Two ATP-consuming molecular machines help balance these processes: TRiC and proteasomes.The eukaryotic chaperonin TRiC/CCT assists the folding of 10%of cytosolic proteins.

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