【摘 要】
：
Aim: 5 Adenosine monophosphate-activated protein kinase (AMPK) was reported to form transcriptional complex with peroxisome proliferator-activated receptor delta (PPARδ) to induce gene expression syne
【机 构】
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Institute of Vascular Medicine and Li Ka Shing Institute of Health Sciences,The Chinese University o
【出 处】
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The 12th Meeting of the Asia Pacific Federation of Pharmacol
论文部分内容阅读
Aim: 5 Adenosine monophosphate-activated protein kinase (AMPK) was reported to form transcriptional complex with peroxisome proliferator-activated receptor delta (PPARδ) to induce gene expression synergistically.This study investigated whether PPARδ mediates the effects of anti-diabetic drug metformin (AMPK activator) in ameliorating ER stress and endothelial dysfunction in high-fat dietinduced obese (DIO) mice.
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