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  5. Functional polymorphisms in cancer stem cell marker gene CD133 predict local recurrence and distant

Functional polymorphisms in cancer stem cell marker gene CD133 predict local recurrence and distant

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户：zxc569148889
【摘 要】
：
Objective: Cancer stem cells (CSCs) are believed to cause local recurrence, distant metastasis, as well as radiotherapy and chemotherapy resistance.We hypothesized that genetic variation in CD 133 (of
【作 者】
：
Qi-Ming Wang Qing-Yi Wei Peng Li Hong-Liang Liu Hui-Hua Xiong Ji Qian Daniel Gomez Zhen-Sheng Liu Li-E Wang Zhong-Xing Liao 
【机 构】
：
Department of Internal Medicine,the Affiliated Cancer Hospital of Zhengzhou University,Henan Cancer
【出 处】
：
22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会)
【发表日期】
：
2013年7期
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Objective: Cancer stem cells (CSCs) are believed to cause local recurrence, distant metastasis, as well as radiotherapy and chemotherapy resistance.We hypothesized that genetic variation in CD 133 (official name, PROM1), one of the most important marker genes of CSCs, may affect clinical outcomes among nonsmall cell lung cancer (NSCLC) patients treated with definitive radiotherapy.
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