The transcriptional coactivator Yes-associated protein(YAP)is frequently found dysregulated in various cancers.The oncogenic activity of YAP is not only controlled by the classic Hippo kinase cascade,
Structures of biological macromolecules play many important biological and physiological roles.However,crystal structure determination of biological macromolecules containing transition-metals and/or
Endophytic fungi have appeared as promising sources of various bioactive natural products due to their complex interactions with the host plants.[1,2] Endophytic fungi of Cephalotaxus fortune from Qin
Our research is focused on in-depth study of bioinspired proton transfer processes in catalysis that lead to discovery of novel modes of catalysis activation and asymmetric control,new catalytic speci