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  5. Mitochondrial tRNAThr Gene Mutation in Maternally Inherited Hypertension and the Regulatory Mechanis

Mitochondrial tRNAThr Gene Mutation in Maternally Inherited Hypertension and the Regulatory Mechanis

来源 :2015中国老年医学和老年健康产业大会 | 被引量 : 0次 | 上传用户：ytcjy
【摘 要】
：
BACKGROUND: Development of essential hypertension (EH) in the offspring has significant correlation with maternal EH.In addition, mtDNA mutations are related with elevated blood pressure, but the unde
【作 者】
：
Y.F.Lan T.Yin Q.L.Zhu J.Yang Z.B.Li Y.Q.Liu J.L.Gao X.P.Wang C.Zhu X.J.Zhao Y.Li 
【机 构】
：
Department of Healthcare, Hainan Branch of Chinese PLA General Hospital,Sanya, 572000, China;Cardiov
【出 处】
：
2015中国老年医学和老年健康产业大会
【发表日期】
：
2015年7期
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BACKGROUND: Development of essential hypertension (EH) in the offspring has significant correlation with maternal EH.In addition, mtDNA mutations are related with elevated blood pressure, but the underlying mechanism is unclear.Based on a study with small sample size and two pedigrees maternal family members, we tried to investigate potential mechanisms of how EH characterized with maternal inheritance was caused by mitochondrial mutations.
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