【摘 要】
：
目的：探讨强直性脊柱炎(ankylosing spondylitis AS)合并颈椎骨折的手术治疗方法及其疗效；方法：对2002-2009年期间,我院收治的13例强直性脊柱炎合并颈椎骨折患者施行颈前路开放复位植骨融合内固定术,并回顾性分析国内外相关文献资料；结果：本组13例患者随访6-48月,脊髓功能Franke分级较术前评价改善0.7级,其中9人有改善,4人无变化,颈椎骨折植骨融合率达到100％
【机 构】
：
华中科技大学同济医学院附属同济医院骨科
论文部分内容阅读
目的：探讨强直性脊柱炎(ankylosing spondylitis AS)合并颈椎骨折的手术治疗方法及其疗效；方法：对2002-2009年期间,我院收治的13例强直性脊柱炎合并颈椎骨折患者施行颈前路开放复位植骨融合内固定术,并回顾性分析国内外相关文献资料；结果：本组13例患者随访6-48月,脊髓功能Franke分级较术前评价改善0.7级,其中9人有改善,4人无变化,颈椎骨折植骨融合率达到100％,文献回顾结果表明：目前对于强直性脊柱炎合并颈椎骨折的患者多倾向于手术治疗,手术方式有前路减压植骨融合术、后路减压植骨融合术以及前后路联合减压植骨融合术,手术后脊髓功能改善率、骨折融合率均优于头颈胸支具固定、Halo-vest外固定术、颅骨牵引术等治疗手段,手术相关并发症主要为切口愈合不良、内置物松动、植骨融合不良以及强直性脊柱炎相关并发症.结论：手术治疗强直性脊柱炎合并颈椎骨折可以提高疗效,但是根据患者原有颈椎畸形程度选择合适的手术入路及恰当的融合固定范围是提高疗效的关键.
其他文献
The identification of peptide epitopes with techniques such as phage display peptide libraries has opened the opportunity to develop specific targeting molecules for a variety of antibody-based biomed
The presentation will provide an overview of the U.S.Food and Drug Administration (FDA) approval process for follow-on biologics under the new U.S.healthcare law; the doctrine of Patent Misuse in the
Molecular Biology is a disruptive technology in the pharmaceutical industry, roiling the established order, creating new paradigms for drug discovery and development, and ultimately for medicine itsel
Approved and investigational therapeutic monoclonal antibodies (mAbs) represent the leading sector of the biopharmaceuticals market and research.However, pursuing mAb affinity and structural similarit
Antibodies have rapidly become a mainstay of therapeutics.The bispecific antibody (bsAb) field has evolved over the past two decades mainly for applications that cannot be easily achieved by monospeci
We have developed two novel antibody formats: Fcabs, in which antigen-binding sites are introduced into a human Fc fragment and mAb2s, in which additional binding sites are engineered into the Fc of a
目的：探讨颈椎后凸畸形的手术治疗方法及其疗效.方法：本组共21例，男9例，女12例；年龄21-72岁，平均49岁；病因：炎症5例，颈椎病3例，后路全椎板切除术后2例，强直性脊柱炎2例，肿瘤或肿瘤样病变5例，陈旧性损伤4例.所有患者术前测量颈椎后凸角评价、评价颈椎柔韧度.根据不同病因、柔韧性、脊髓压迫情况等因素采用单纯前路、单纯后路或前后路联合手术，术后随访时间18-96个月，术后疗效评价包括颈椎后
目的：通过对颅底凹陷症的解剖学观察和测量,提出一种实用的分类方法；方法：70例颅底凹陷症患者,行颅骨正侧位摄片及包含颅底部的颈椎CT扫描和头颈部MR检查,根据有无寰枢椎脱位分为稳定型和不稳定型2类.分别统计两种类型颅底凹陷症患者合并寰枕融合畸形、Chari畸形,枢椎上关节面倾斜及脊髓空洞等的例数.并测量斜坡角(α),齿突顶点到Chamberlain线的距离(a),齿突顶点到枕骨大孔的距离(b)等参
Transarticular screw (TAS) fixation has been commonly used for posterior C1-C2 arthrodesis in both traumatic and non-traumatic lesions.Anterior transarticular screw fixation C1-2 is a less invasive te
Purpose: Atlantoaxial fixation techniques using anterior and posterior aflantoaxial transarticular screws have promising clinical results.However, few reports have compared the anatomical risk of vert