【摘 要】
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Introduction: In order to substantiate that PELD is a less traumatic procedure, and therefore has a lower surgical stress response compared to OD.The purpose of this study is to compare the overall ef
【出 处】
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第六届中国微创脊柱外科学术会议暨第一届中美微创脊柱高峰论坛
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Introduction: In order to substantiate that PELD is a less traumatic procedure, and therefore has a lower surgical stress response compared to OD.The purpose of this study is to compare the overall effects of surgical trauma and surgical results resulting from PELD and OD.Materials and Methods: The patients will randomly allocated into two groups, the PELD and OD groups.Each group will collect 10 patients.The indications for surgery is patient with symptomatic lumbar disc herniation who failed to respond to conservative treatment for 3 months.Blood loss, hospital stay, and skin incision size will be recorded in these two groups.In this study, a quantitative comparison will be performed through analyzing patient systemic cytokines, CPK and CRP response.An enzyme-linked immunosorbent assay (ELISA) is used for serum levels of Interleukin-1beta(IL-1beta), Interleukin-6 (IL-6), and Interleukin-8(IL-8), Interleukin 10(IL-10) and will be measured before surgery and at 1,6,12 ,24 and 48h after surgery.
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