2. 您的位置
3. 首页
4. 会议论文
5. A novel strategy of use neutrophiles as innate Trojan horses for delivery of therapeutic PLGA nanopa

A novel strategy of use neutrophiles as innate Trojan horses for delivery of therapeutic PLGA nanopa

来源 :2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 | 被引量 : 0次 | 上传用户：yanghong098

【摘 要】

：

How to efficiently transport systemic drug delivery vehicles targeting to tumors is one of the important goals for cancer therapy.Recently,whether passive or active target preparations,upon entering t

【作 者】

：

Jifu Hao Meixiang Wang Jing Zhao Qiannan Zhuang Te Han Hua Tang 

【机 构】

：

College of Pharmacy,Taishan Medical University,Taian 271016,PR China

【出 处】

：

2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年

【发表日期】

：

2016年4期

【关键词】

：

PLGA pacliatxel neutrophiles tumor targeting 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　How to efficiently transport systemic drug delivery vehicles targeting to tumors is one of the important goals for cancer therapy.Recently,whether passive or active target preparations,upon entering the blood,cannot evade the clearance fate in vivo and then removed by the mononuclear phagocyte system.

其他文献

A tricky strategy for efficient orally-delivered nanoparticles through the modulation of surface “hy

会议

nanoparticlesmucusepitheliumhydrophilicityhydrophobicityoral delivery

Cytosolic co-delivery of miRNA-34a and docetaxel by core-shell nanocarriers for synergistic breast c

Breast cancer is the leading cause of cancer death in women worldwide,and metastasis-related recurrence accounts for over 90%of treatment failure clinically.Co-delivery of microRNAs(miRNAs)and chemoth

会议

Core-shell nanocarrierscytosolic co-deliverymiRNA-34adocetaxelsynergistic br

Determination of Nucleosides in Cordyceps sinensis by HPLC

OBJECTIVE To simultaneously determine the contents of guanine,thymine,adenine,adenosine and cordycepin in Cordyceps sinenis by the RP-HPLC method.

会议

Cordyceps sinensisHPLCNucleosidesDetermination

Dual-Sensitive and Core-crosslinked block Polymeric Micelles for Cancer Therapy

The utilization of polymeric micelles has demonstrated great potential in delivering anticancer drugs.However,it should be noticed that the untimely disassembly of general polymeric micelles leads to

会议

pH-responsive de-PEGylated nanoparticles based on triphenylphosphine-quercetin self-assemblies for m

In cancer treatment,a high efficient mitochondria-targeted drug delivery remained challenged for decades.In this study,we engineered mitochondria-targeted self-assembled nanoparticles based on amphiph

会议

Stepwise pH-responsive nanoparticles for enhanced cellular uptake and on-demand intracellular releas

Physicochemical properties,including particle size,zeta potential,and drug release behavior,affect the targeting efficiency,cellular uptake,as well as antitumor effect of nanocarriers in a formulated

会议

stepwise pH-responsivecharge reversalon-demand drug releaseEfficient delivery

The modeling and application of a 3D tumor cell culture system

Objective To make a variety of porous scaffolds which can mimic tumor micro environmental conditions followed with cytology in vitro test research on the cells grown in the 3D scaffolds.

会议

3DSilkfibroinChitosanporous scaffoldMicroenvironmentStructural characteris

ROS-Sensitive Peptide-Conjugated chitosan derivative for targeting therapy of breast cancer

Objective: To prepare multifunctional nanoparticles loading with Dox and siRNA by synthesized N,N,N-trimethyl chitosan chloride(TMC)decorated with boronic acid(NBC)and HAIYPRH peptide.

会议

Innovative co-delivery system of siRNA and Doxorubicin aimed to reversal multidrug resistance via su

P-glycoprotein(P-gp)plays an importantrole in multi-drug resistance(MDR),proved to be one of the major obstacles in cancerchemotherapy.Cationic polymerscould specifically deliver siRNA to tumor cells

会议

cationic triblock copolymersiRNAmultidrug resistancemicelle

Experimental study on the construction and properties of chitosan derivatives

Objectives: The purpose of this study was to establish Berberine(Ber)nanoparticles(NPs)prepared by ionic cross-linking method.In this sustained release drug delivery system(DDS),Ber was used as a mode

会议

BerberineChitosanHTCCNanoparticles