Bacterial porins are water-filled β-barrel channels that allow translocation of solutes across the outer membrane.They feature a constriction zone,contribu
Innovate drug discovery relies on the identification of new drug targets and lead compounds.However,traditional experimental methods hardly satisfy the dema
2,4,6-trinitrotoluene(TNT)and its byproducts Drinitrotoluene(DNT)pose a significant risk to human health and other living organisms.Nowadays,the existing qu
Organophosphatecompounds(OPs)are most toxic insecticides used today,adversely affecting the human nervous system even at low levels of exposure.They have lo
P21-activated kinase 4(PAK4),a serine/threonine protein kinase,was originally identified as an effector protein for Rho-family GTPases.1 PAK4 plays an impor