EFFECTS OF VALSARTAN ON EXPRESSION OF GP130 IN CARDIAC HYPERTROPHY RAT INDUCED BY ANG Ⅱ

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：qq104397622

【摘要】

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【作者】

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Chai Chanjuan Yng Zhiming

【机构】

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Department of Cardiology,The Second Hospital of Shanxi Medical University

【出处】

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第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

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2013年2期

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Objectives To observe effects of valsartan on expression of gp130 in cardiac hypertrophy rat induced by Ang Ⅱ.Methods Neonatal rat cardiomyocyte induced by Ang Ⅱ into cardiac hypertrophy, and cultivated with different concentrentions of valsartan, used phase contrast microscope to measure transdiameter of cardiomyocyte, the protein synthesis rate was measured by 3H-leucine incorporation;The expression of gp130 mRNA and protein were determined by reverse transcriptionpolymerase chain reaction (RT-PCR) and western-blot.

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EFFECTS OF VALSARTAN ON EXPRESSION OF GP130 IN CARDIAC HYPERTROPHY RAT INDUCED BY ANG Ⅱ

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