论文部分内容阅读
目的：转移导致乳腺癌患者死亡的首要因素，血行转移是肿瘤转移的最重要的方式之一。以往研究显示，在肿瘤血行转移过程中，血小板可粘附于肿瘤细胞表面，保护肿瘤细胞免受血流的机械损伤和免疫攻击，并协助肿瘤细胞在远隔部位定植。
斑蝥素去甲斑蝥素通过PKC/整合素α2通路抑制乳腺癌细胞与血小板粘附的机制研究
【摘 要】
：
目的：转移导致乳腺癌患者死亡的首要因素，血行转移是肿瘤转移的最重要的方式之一。以往研究显示，在肿瘤血行转移过程中，血小板可粘附于肿瘤细胞表面，保护肿瘤细胞免受血流的机械损伤和免疫攻击，并协助肿瘤细胞在远隔部位定植。
【机 构】
：
苏州 苏大附一院肿瘤科 苏州 苏州吴中人民医院肿瘤科
【出 处】
：
第十八届全国临床肿瘤学大会暨2015年CSCO学术年会
【发表日期】
：
2015年4期
其他文献
目的 临床总结分析重睑及内眦手术的相关问题方法 回顾性分析了1600例重睑(约1400同期内眦开大)手术，该组病例于2014年1月至2015年6月收治.其中150例为修复手术.重睑的手术或修复术均采用切开法，其中80例采用三点或四点的微创缝合方法.内眦开大手术1300例采用沿睑缘的L型方法.100例采用Z成型术.根据上睑皮肤、眼轮匝肌后脂肪、眶上缘的位置决定眼轮匝肌的去除量或皮下的固定与否.在埋线
会议
Objective: To investigate the expression of microRNA-425-5p in gastric cancer patients specimens and cell lines;To investigate the up-regulation and down-regulation of microRNA-425-5p on gastric cance
T2DM susceptible HHEX rs1111875 and rs7923837 variants are associated with CRC Risk independent on t
Objective: To investigate the association of the genetic polymorphisms in HEEX gene, a DM promoting hereditary factor, and the susceptibility and progression of CRC.
Implications for Determining The Optimal Treatment for Locally Advanced Rectal Cancer in Elderly Pat
Objective: Patients were excluded if they were older than 75 years of age in most clinical trials.Thus, the optimal treatment strategies in elderly patients are still controversial.
Objective: Our previous study indicated that a preoperative CTC≥2 was an independent prognosticator for early recurrence in hepatocellular carcinoma (HCC).Recurrent foci developed in these patients we
A Phase Ⅰ/Ⅱ Study of Concurrent S-1 and Intensity Modulated Radiotherapy as Adjuvant Treatment for L
Objective: This phase Ⅰ/Ⅱ trial aimed to determine the maximum tolerated dose (MTD) and toxicity profile of S-1 with concomitant intensity modulated radiotherapy (IMRT) as an adjuvant treatment for lo
Intratumoral α-SMA Enhances the Prognostic Potency of CD34 Associated with Maintenance of Microvesse
Objective: Microvessel density (MVD) as an angiogenesis predictor is inefficient per se in cancer prognosis.We evaluated prognostic values of combining intratumoral alpha-smooth muscle actin (α-SMA)-p
Objective: Loss of DCP4 plays a key role in the development of colorectal cancer.Recent studies demonstrated that ectopically expressed miRNAs is another important factor which lead to DCP4 inactivati
Objective: Our aim was to determine impact of negative to positive lymph node ratio (NPR) on oncological outcomes in a series of patients with stage Ⅲ colorectal cancer.
Outcome and prognostic analysis in patients receiving IMRT-based neoadjuvant chemoradiotherapy for t
Objective: To analyze the outcome, as well as the prognostic factors in thoracic esophageal squamous cell carcinoma patients who received the IMRT-based neoadjuvant chemoradiotherapy followed by surge