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  5. Donor CD8+ T cells preferentially damaged thymic mTEC and caused defective thymic selection early af

Donor CD8+ T cells preferentially damaged thymic mTEC and caused defective thymic selection early af

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：QUFENGJUN
【摘 要】
：
(1)Donor CD8+ T cells preferentially damaged thymic mTEC early after HCT.Lethally irradiated BALB/c recipients were transplanted with donor C57BL/6 TBCD-BM(2.5 x 106)and 0.1 x106 donor CD4+ or CD8+ T
【作 者】
：
Tao Wu James Young Heather Johnston Xiong Ni Ruishu Deng Hai Bai Cunbang Wang Jianmin Wang Defu Zeng 
【机 构】
：
Hematology Department of Lanzhou General Hospital,Lanzhou Command,Lanzhou,730050
【出 处】
：
The 35th World Congress of the International Society of Hema
【发表日期】
：
2014年5期
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(1)Donor CD8+ T cells preferentially damaged thymic mTEC early after HCT.Lethally irradiated BALB/c recipients were transplanted with donor C57BL/6 TBCD-BM(2.5 x 106)and 0.1 x106 donor CD4+ or CD8+ T cells.At 15 days after HCT,recipient thymus was measured for the percentage and yield of thymic medullary epithelial cells (mTEC).
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