Cornel iridoid glycoside protects against white matter lesions induced by cerebral ischemia via acti

来源 :2019全国老年痴呆与认知障碍相关疾病学术大会 | 被引量 : 0次 | 上传用户：gyl722

【摘要】

：

Ischemic stroke often elicits profound white matter lesions,which results in poor neurological outcomes and impairing the recovery in post-stroke.

【作者】

：

WANG Ming-yang HUA Xue-si NIU Hong-mei SUN Zheng-yu ZHANG Li LI Ya-li ZHANG Lan LI Lin

【机构】

：

Department of Pharmacy,Xuanwu Hospital of Capital Medical University,Key Laboratory for Neurodegener

【出处】

：

2019全国老年痴呆与认知障碍相关疾病学术大会

【发表日期】

：

2019年10期

【关键词】

：

cornel iridoid glycoside white matter lesions cerebral ischemia brain-derived ne

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Ischemic stroke often elicits profound white matter lesions,which results in poor neurological outcomes and impairing the recovery in post-stroke.

其他文献

Inhibition of 6-phosphogluconate dehydrogenase reverses cisplatin resistance in ovarian and lung can

Cisplatin is currently one of the most effective chemotherapeutic drugs for the treatment of ovarian and lung cancer.Whereas,resistance to cisplatin is common and it often leads to local and distant f

会议

Oct4自噬性降解促进肿瘤干细胞分化的分子机制

会议

Novel anti-AD dimeric leads:from relieving symptoms to modifying diseases via multi-targets

Alzheimer disease(AD)has now become the most common brain disorder among the older population.In addition,the currently existing therapeutics only offer temporary symptomatic relieves.

会议

Alzheimer diseasedimeric leadsmulti-targetsrelieving symptomsmodifying disea

Advances in extracellular space and immunotherapy of pre-clinical stage of Alzheimer disease

The most common age-related neurodegenerative disease is Alzheimer disease(AD),the imbalance between Aβ generation and clearance accumulated in extracellular plaques(ECS).

会议

Alzheimer diseaseextracellular plaquesimmunotherapyAβ clearanceautophagy

Implication of lipoprotein lipase-deficient impaired learning and memory:focus on aging and testoste

OBJECTIVE Normal male aging is associated with declines in levels of the sex steroid hormone testosterone.A large body of evidence supports a neurotrophic role for testosterone in central nervous syst

会议

lipoprotein lipasesex steroid hormonesDNA methylationhomeostatic regulation

Scalp mechanical stimulation promotes moderate vasodilation and the permeability of blood-brain barr

OBJECTIVE Scalp mechanical stimulation,like combing,is one of the useful methods to keep brain health,which was historically recorded in traditional Chinese medicine thousand years ago.

会议

blood-brain barriercapillarycombingdextran

Physalin B reduce secretion of Aβ by inhibiting phosphorylation ofSTAT3 via down-regulated expressio

OBJECTIVE Extracellular amyloid-β(Aβ)plaques are one of the major pathological hallmarks of Alzheim-er disease(AD).Therefore,decreasing Aβ levels is one strategyfor preventing the etiology of AD.

会议

Alzheimer diseasePhysalin Bβ-amyloid proteinBACE1PS1STAT3

Neuroprotective profiles of anti-aging gene Klotho inAlzheimer disease mouse model

OBJECTIVE Alzheimer disease(AD)is the most common type of senile dementia.The anti-aging gene Klotho is reported to decline in the brain of patients and animals with AD.

会议

KlothoAlzheimer diseaseAPP/PS1 transgenic mouse

Active fraction combination from Liuwei Dihuang decoction(LW-AFC)ameliorates corticosterone-induced

Liuwei Dihuang decoction(LW),a classic formula in traditional Chinese medicine(TCM),has been used for nearly one thousand years for various diseases with characteristic features of kidney yin deficien

会议

LW-active fraction combinationactive fractionscorticosteronelong-term potenti

Ellagic acid supports neurons by regulating astroglia nuclear factor erythroid 2-related factor 2

OBJECTIVE Astroglia support neurons by providing substrates for neuronal metabolism,glutamate clear- ance and anti-oxidant protection.

会议

ellagic acidastrogliaNrf2neurotrophic effects

Cornel iridoid glycoside protects against white matter lesions induced by cerebral ischemia via acti

与本文相关的学术论文