2. 您的位置
3. 首页
4. 会议论文
5. Dexmedetomidine, a sedative/anesthetic and neuroprotective drug, acts via astrocytic α2-adrenergic r

Dexmedetomidine, a sedative/anesthetic and neuroprotective drug, acts via astrocytic α2-adrenergic r

来源 :2nd International Neural Regeneration Symposium(INRS2012)(第二 | 被引量 : 0次 | 上传用户：sssmickey

【摘 要】

：

Dexmedetomidine, a sedative/anesthetic drug is associated with a lower incidence of delirium and reduced length of ventilation after severe brain trauma.Dexmedetomidine has neuroprotective effects aga

【作 者】

：

Meixia Zhang Xiaolei Shan Li Gu Ye Chen Leif Hertz Liang Peng 

【机 构】

：

Department of Clinical Pharmacology, China Medical University, Shenyang 110001, Liaoning Province, C

【出 处】

：

2nd International Neural Regeneration Symposium(INRS2012)(第二

【发表日期】

：

2012年8期

【关键词】

：

astrocyte cerebellar granule neuron epidermal growth factor receptor H2O2 transa 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Dexmedetomidine, a sedative/anesthetic drug is associated with a lower incidence of delirium and reduced length of ventilation after severe brain trauma.Dexmedetomidine has neuroprotective effects against ischemia and may protect against trauma in hippocampal organotypic cultures.

其他文献

Neural stem cells overexpressing brain-derived neurotrophic factor improve cell survival through Ras

Our previous studies indicated that the transplantation of rat embryonic-derived neural stem cells (NSCs) overexpressing brain-derived neurotrophic factor (BDNF) (BDNF/NSCs) caused overexpression of B

会议

brain-derived neurotrophic factorRas/Raf/Erk1/2 pathwayneural stem cellstraum

Upregulation of Wnt7b expression in the hippocampus of adult rats after focal cerebral ischemia

Neurogenesis persists in the adult mammalian brain and can be regulated by physiological and pathological events, including stroke.

会议

Wnt7b5-bromo-2'-deoxyuridine-5'-monophosphate labelingsubgranular zo

Neuroprotective effects of three compounds on neurons exposed to oxygen glucose deprivation in vitro

Hypoxia/ischemia induces neuronal death.Ways to protect neurons from death under the conditions of hypoxia/ischemia have been widely studied.

会议

oxygen glucose deprivationneuronshypoxia/ischemiacompoundsM1M2chinonin

Involvement of ERK2 and Calpain 1 signaling pathways and their cross-talk in pathophysiology of spin

Calpain (μ-and m-) and ERK1/2 activation are strongly implicated in the pathophysiology of traumatic spinal cord injury (SCI).However, the contribution of either individual calpain/ERK isoforms or cro

会议

spinal cord injurycalpainERK1/2

Schwann cells exhibit long-lasting survival and promote axon and vascular growth following transplan

Traumatic spinal cord injury (SCI) follows a two-phase pathological progression, starting with primary mechanical damage followed by secondary biochemical injury that expands the lesion over time.Foll

会议

spinal cord injurySchwann cell transplantationaxon regeneration

Transplantation of human umbilical cord blood or amniotic epithelial stem cells relieves central neu

Stem cell therapy is a potential treatment for spinal cord injury (SCI) and a variety of different stem cell types have been grafted into humans suffering from spinal cord trauma or into animal models

会议

cell transplantationhuman umbilical cord bloodamniotic epithelial stem cellsc

Injury potential modulation by electrical stimulation after spinal cord injury in rats

Injury potential is a direct current potential difference between sites of spinal cord injury and normal tissue, and its initial amplitude is a significant indicator of the grade of spinal cord injury

会议

spinal cord injuryinjury potentialelectrical stimulation

Regulatory effects of macrophages on the microenvironment in the damage zone after spinal cord injur

Mouse bone marrow-derived macrophages and fetal brain-derived microglia were isolated and cultured in vitro, then administered myelin, a dominant proinflammatory mediator released after spinal cord in

会议

spinal cord injurymacrophagesmyelinmicroenvironment

Pluronic-F-127 temperature-sensitive hydrogel composite transplantation of Lingo-1 RNAi promotes ner

Lingo-1 is selectively expressed in oligodendrocytes and neurons in the central nervous system (CNS), and is a key negative regulator of nerve regeneration.

会议

spinal cord injuryPluronic F-127 hydrogelLingo-1 RNA interferencefunctional r

Changes in densities of spinal interneurons in mutant mice with congenital defects of corticospinal

Interneurons may play an important role in functional compensation and axonal regeneration after spinal cord injury.However, the mechanism underlying functional recovery is unclear.

会议

spinal interneuronsmutant micecongenital defectscorticospinal tractsNeuNcho