【摘 要】
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Objective We revealed the changes of catecholamine(CA) and lactate levels in myocardial interstitial fluid during cardiopulmonary resuscitation, tried to prove the pharmacological effects of sildenafi
【机 构】
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Department of Emergency, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, Ch
【出 处】
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中华医学会急诊医学分会第十八次全国急诊医学学术年会
论文部分内容阅读
Objective We revealed the changes of catecholamine(CA) and lactate levels in myocardial interstitial fluid during cardiopulmonary resuscitation, tried to prove the pharmacological effects of sildenafil pretreatment to myocardial protection.Interventions Twenty-four pigs were randomly divided into three groups: a saline group (SA group), a sildenafil group (Sil group) and a shame operation (SHAM group) (n=8 each).Before ventricular fibrillation (VF) was induced, sildenafil was given once intraperitoneally at a dose of 0.5 mg/kg 40 min prior to VF.
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