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  5. PEI modified biodegradable complex micelles as gene transfer vector for proliferation of ECs

PEI modified biodegradable complex micelles as gene transfer vector for proliferation of ECs

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：XIAOZHOU914
【摘 要】
：
Polyethylenimine (PEI) is one of the most successful cationic polymers for gene delivery.PEI of high molecular weight provides high transfection efficiency but at the same time a high cytotoxicity,whi
【作 者】
：
Juan Lv Xuefang Hao Jing Yang Yakai Feng Marc Behl Andreas Lendlein 
【机 构】
：
School of Chemical Engineering and Technology,Collaborative Innovation Center of Chemical Science an
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
【发表日期】
：
2014年6期
【关键词】
：
gene vector PEI complex micelles biodegradable endothelial cells 
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　　Polyethylenimine (PEI) is one of the most successful cationic polymers for gene delivery.PEI of high molecular weight provides high transfection efficiency but at the same time a high cytotoxicity,while the toxicity of low molecular weight PEI is significantly lower,however its transfection efficiency as well.It is reported that the copolymerization of PEI with other polymers could enhance the transfection efficiency.
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