Engineering natural membrane vesicles exosomes as multifunctional drug delivery platform for targete

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：myazx

【摘要】

：

【作者】

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Yanhua Tian Xin Tian Motao Zhu Yuliang Zhao Guangjun Nie

【机构】

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National Center for Nanoscience and Technology,China,Beijing 100190,China

【出处】

：

International Conference on Nanoscience & Technology,China 2

【发表日期】

：

2013年3期

【关键词】

：

exosome iRGD doxorubicin tumor therapy

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　　Targeted drug delivery vesicles with low immunogenicity and toxicity are urgently needed for clinically used anti-tumor drugs for an enhanced tumor therapy while reduced side effect.We introduced a promising natural membrane shuttle-exosome, for the targeted delivery of either doxorubicin, siRNA or tumor vaccines to cancer cells.Exosomes are nano-sized membrane vesicles secreted by numerous cell types after fusing of multivesicular bodies (MVBs) with plasma membrane.

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Engineering natural membrane vesicles exosomes as multifunctional drug delivery platform for targete

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