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5. Natural product inspired design and synthesis of molecular hybrids based on Largazole and Psammaplin

Natural product inspired design and synthesis of molecular hybrids based on Largazole and Psammaplin

来源 :2016年长三角药物化学研讨会 | 被引量 : 0次 | 上传用户：kasuo11111111

【摘 要】

：

Since SAHA (2006),Belinostat (2014),Panobinostat (2015),Chidamide and Romidepsin (FK228,2010) were approved for the treatment of cutaneous T-cell lymphoma,inhibition of histone deacetylases (HDACs) ha

【作 者】

：

Bingbing Zhang Xiaoling Yu Xinsheng Lei 

【机 构】

：

School of Pharmacy, Fudan University, Shanghai, 200032

【出 处】

：

2016年长三角药物化学研讨会

【发表日期】

：

2016年11期

【关键词】

：

Largazole Depsipeptide Natural Product HDACs Inhibitor 

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论文部分内容阅读

　　Since SAHA (2006),Belinostat (2014),Panobinostat (2015),Chidamide and Romidepsin (FK228,2010) were approved for the treatment of cutaneous T-cell lymphoma,inhibition of histone deacetylases (HDACs) have became a validated approach to the treatment for cancer.

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