【摘 要】
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Emerging evidence suggests that microRNAs (miRNAs) play a critical biological role in a variety of pathophysiological processes by suppressing their target genes.However, the precise contribution of m
【机 构】
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Department of Occupational Medicine and Environmental Health, School of Public Health, Nanjing Medic
【出 处】
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《人造化学物毒理学和流行病学》中德国际论坛
论文部分内容阅读
Emerging evidence suggests that microRNAs (miRNAs) play a critical biological role in a variety of pathophysiological processes by suppressing their target genes.However, the precise contribution of miRNAs in fibrotic lung diseases, especially Coal Workers Pneumoconiosis (CWP), remains poorly understood.To identify miRNAs with potential roles in lung fibrogenesis, total RNA was isolated from mice lungs collected at day 0, day 3, day 7, day 14, day 28 and day 56 after silica exposure.Then, miRNA microarray was performed with one mouse lung at each time point.
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