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  5. Regulatory axis of miR-195/497 and HMGA1/Id3 governs muscle cell proliferation and differentiation

Regulatory axis of miR-195/497 and HMGA1/Id3 governs muscle cell proliferation and differentiation

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：shinboy_zsl
【摘 要】
：
Myocytes withdraw from the cell cycle to differentiation during muscle development.Given the capacity of microRNAs(miRNAs)regulating gene expression and during development,we screened for miRNAs that
【作 者】
：
Zhixiong Tang Huiling Qiu Jiasheng Zhong Lan Luo Nian Liu Yueran Li Deming Gou 
【机 构】
：
Shenzhen Key Laboratory of Microbial Genetic Engineering,College of Life Sciences,Shenzhen Universit
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
miR-195 miR-497 proliferation differentiation 
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　　Myocytes withdraw from the cell cycle to differentiation during muscle development.Given the capacity of microRNAs(miRNAs)regulating gene expression and during development,we screened for miRNAs that were muscle development-associated.Spoly(T)plus analysis of 273 miRNAs revealed 14 miRNAs were strongly upregulated with age of postnatal muscle development in vivo,including miR-195 and-497.
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