• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Quantitative Study of Protein Corona on Gold Nanoparticles with Different Surface Modifications

Quantitative Study of Protein Corona on Gold Nanoparticles with Different Surface Modifications

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：jenny18
【摘 要】
：
Protein corona provides the biological identity for all nanoparticles in vivo.Here we have used dynamic light scattering (DLS) and transmission electron microscopy (TEM) to investigate bovine serum al
【作 者】
：
Menghua Cui Liming Xie 
【机 构】
：
National Center for Nanoscience and Technology,China,Beijing 100190,China
【出 处】
：
International Conference on Nanoscience & Technology,China 2
【发表日期】
：
2013年3期
【关键词】
：
gold nanoparticles protein corona adsorption surface modifications 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Protein corona provides the biological identity for all nanoparticles in vivo.Here we have used dynamic light scattering (DLS) and transmission electron microscopy (TEM) to investigate bovine serum albumin (BSA) and transferrin (TRF) adsorption on gold nanoparticles (AuNPs) with different surface modifications (citrate, thiolglycolic acid, cysteine).DLS revealed protein coronas of one to two protein layers with microscopic dissociation constants in the range of 10-s to 10-6 M.TEM imaging revealed protein corona thickness of 2-5 nim, indicating hard coronas with one protein layer.Surface modification was found to affect protein adsorptions.AuNPs with cysteine ligands (-COO-plus-NH3+ surfacegroups) showed higher affinity with BSA and aggregation with TRF.
其他文献
Self-powered ultraviolet photodetector based on single ZnO microwire/p-Si double heterojunctions
Recently, self-powered devices based on a p-n heterojunction were frequently reported, but there were few report about self-powered UV detectors based on single ZnO microwire/p-Si double heterojunctio
会议
double heterojunctionsself-poweredUV detectorZnO microwire
A Test Method Based on Single-Photon Detection for the Nanocircuits using GaN material
In recent years, the complexity of nanocircuits is continually growing, the increase in nanoeircuit complexity also raises the difficulty in test nanocireuits for fabrication defects.The failure analy
会议
NanocircuitsGaN materialtest methodfailure analysisfault detection
Strain Sensor Based on chromium Nanoparticles Array
High sensitive strain sensors have been fabricated by depositing chromium nanoparticles between silver interdigital electrodes on the substrate of flexible plastic material like polyethylene terhthala
会议
nanoparticles arrayquantum tunnelingstrain sensor
Automated Teflon Microfluidic Peptide Synthesizer
Microfluidic reactors for biomolecule synthesis have many advantages over conventional bulk reactors.Hard materials, such as glass and silicon, often limit the designs of microchips because the contro
会议
microfluidicTeflonpeptide
One-Device Circuit System for Logic Gate Functions Realization
The logic circuits are one of the key components in nanoelectronics.While great efforts have been spared to shrink the size of transistors, the structure and design of the logic circuits, which contai
会议
New Functional Carbon Based Nanomaterials for Biomedical Imaging Applications
We report hereby our recent advances towards the design and synthesis of hierarchic nanohybrids based on biocompatibile carbon nanotubes having the ability to target cancer cells.A novel synthetic met
会议
Carbon nanotubes-D-glucanBiotin-boronic acid fluorophorePET fluorescent senso
Synergistic Inhibition of Breast Cancer Metastasis by Silibinin-Loaded Lipid Nanoparticles Containin
Tumor metastasis is the leading came of breast cancer-related mortality and remains to be the principal obstacle for the successful chemotherapy of breast cancer.To block metastasis of breast cancer,
会议
MetastasisSilibininTPGSNanoparticlesBreast cancer
In vivo assessment of hepatotoxicity, nephrotoxicity and biodistribution using 3-aminopropyltriethox
The biocompatibility and biodistdbution of magnetic nanoparticles (MNPs) in vivo are essential to ensure their safe clinical use.We have studied these aspects with our 3-aminopropyltdethoxysilanc-coat
会议
magnetic nanoparticlesbiocompatibilitymagnetic induction hyperthermiabiodistr
Au@PtAg core/shell nanorods: tailoring enzyme-like activities via alloying
Pt nanoparticles (NPs) have been reported to demonstrate four kinds of enzyme-like activity including superoxide dismutase (SOD), catalase, oxidase and peroxidase.Some of these activities interfere wi
会议
platinumsilveralloycore-shellenzyme-like activitybiodetection
Epidermal Growth Factor-Ferritin H-Chain Nanoparticles as Nanocarrier of Doxorubicin for Overcoming
The emergence of drug-resistant cancer cells together with the toxicity side effect of chemotherapy agents are the major obstacle in cancer treatment.The main purpose of this study is to assess the po
会议
epidermal growth factornanocarrierdoxorubicindrug resistancebreast cancer