• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Estrogen caused a calcium rise via activation of the G protein-coupled estrogen receptor in SH-SY5Y

Estrogen caused a calcium rise via activation of the G protein-coupled estrogen receptor in SH-SY5Y

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：a391137182
【摘 要】
：
The G protein-coupled estrogen receptor 1 (GPER1,also known as GPR30),is a Gs or Gi/o coupled GPCR and has been reported to bind 17β-estradiol (E2) to mediate the non-genomic estrogenic responses.GPER
【作 者】
：
Xiaowei Ding Po Gao Li Dong Qian Li Guohua Zhang Weifang Rong 
【机 构】
：
Department of Physiology,Shanghai Jiaotong University School of Medicine,Shanghai,China,200025
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
【发表日期】
：
2014年7期
【关键词】
：
Estrogen G protein-coupled estrogen receptor intracellular calcium SH-SY5Y cells 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　The G protein-coupled estrogen receptor 1 (GPER1,also known as GPR30),is a Gs or Gi/o coupled GPCR and has been reported to bind 17β-estradiol (E2) to mediate the non-genomic estrogenic responses.GPER1 has been detected in several brain regions,including the hypothalamus,the brainstem and the spinal cord.
其他文献
Effects of Different Intervention Methods on the Protein Expression of ER and ERRα in the Uterus of
Objective The aim of this study was to compare the effects of different intervention methods on the protein expression of estrogen receptor(ERα,ERβ)and estrogen receptor related receptor α(ERRα)in the
会议
Ovariectomized ratsEstrogen receptorWhole-body vertical vibrationGenisteinTr
Cystathionine β-synthase and cystathionine γ-lyase regulate VEGF and sFlt-1 production in human plac
Imbalance release of proangiogenic and antiangiogenic factor from placenta causes maternal endothelial dysfunction,the main manifestation of preeclampsia (PE).Recently,hydrogen sulfide (H2S) has been
会议
hydrogen sulfidecystathionine β-synthasecystathionine γ-lyase regulatevascula
Accentuation of ANP secretion by physcion via L-type Ca2+ channels in isolated perfused beating rabb
Objective:Physcion,an active anthraquinone constituent isolated from the rhubarb,a traditional Chinese herbal medicine which is widely used in clinical treatment,has cardiovascular protective properti
会议
Physcionatrial natriuretic peptidesecretionL-type Ca2+channelsatrial dynamic
花生四烯酸细胞色素P450ω-羟化酶4A14在小鼠肝脏脂质代谢中的作用
目的：随着人们生活水平的提高，我国非酒精性脂肪肝的发病率越来越高。本文旨在探讨细胞色素P450 ω-羟化酶CYP4A14 在肝脏脂质代谢中的作用，以期为阐明非酒精性脂肪肝发生的机制提供线索。方法：(1)野生型(WT)及CYP4A14 基因敲除(4A14KO)小鼠分为如下四组：1)WT+普通饮食组；2)WT+高脂饮食组；3)4A14KO+普通饮食组；4)4A14KO+高脂饮食组。
会议
CYP4A14非酒精性脂肪肝FAT/CD36
内源性硫化氢抑制子宫激活的机制
目的：硫化氢(H2S)是近年来发现的第三类气体信号分子,在体内发挥包括抗炎在内的多种生物学功能。人类分娩是一个炎症过程,分娩前夕炎性因子参与激活子宫。人类妊娠子宫平滑肌能够表达H2S 合成酶CSE 和CBS,且足月临产组H2S 合成酶的表达量明显低于足月未临产组,提示内源性H2S 可能参与抑制子宫激活。
会议
硫化氢子宫激活炎性因子子宫收缩相关蛋白信号转导通路
Time course study of nesfatin-1 expression in hypothalamus and gastric mucosa in type 2 diabetic mic
Objective:The purpose is to investigate the changes of nesfatin-1 expression in brain (hypothalamus) and peripheral tissues (gastric mucosa and plasma) during the pathophysiological course of type 2 d
会议
Nesfatin-1T2DMHypothalamusFood intakeFFA
Increased circulating levels of betatrophin in patients with type 2 diabetes and gestational diabete
Objective:The aim of this study was to explore serum betatrophin levels in health pregnant or gestational diabetes women,and patients with type 2 diabetes.We provided a better understanding of the phy
会议
BetatrophinT2DMGDMPregnant woman
Adiponectin Enhances Acetylcholine-induced Aortic Relaxation After Angiotensin Ⅱ-induced Vasoconstri
Background: Hypertension is a major risk factor for cardiovascular disease,a significant cause of worldwide morbidity and mortality.The association between adiponectin(APN,the most abundant secreted p
会议
AdiponectinAcetylcholineAngiotensin ⅡVasoconstriction
NMDA长时间处理小鼠胰腺β细胞MIN6导致细胞功能紊乱
NMDA 受体是中枢神经系统内的离子型谷氨酸受体,近年研究显示,该受体亦广泛分布于多种外周非神经组织,包括胰岛细胞。研究报道,NMDA 受体的过度激活对神经和非神经组织具有毒性作用。本室前期研究发现在整体动物水平上,NMDA 受体的过度激活可损伤小鼠胰岛的功能。
会议
NMDAMIN6 β-cell细胞功能
Akt1和Akt2在小鼠卵母细胞减数分裂恢复过程中定位及表达的差别
PI3K/Akt 信号途径在细胞生理学的许多信号转导级联反应中起着重要的枢纽作用，然而蛋白激酶B(PKB/Akt)三个亚型的不同生理学功能尚不十分清楚。我们以前的研究报道了Akt 三个亚型在受精卵中的表达，本研究，我们观察了Akt1 和Akt2 在小鼠卵母细胞减数分裂恢复过程中定位及表达的区别。
会议
蛋白激酶α(PKBα/Akt1)蛋白激酶Bβ(PKBβ/Akt2)卵母细胞小鼠减数分裂恢复