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Delirium is a common occurrence following cardiac surgery.Our discussion will focus on the detection of delirium both in the acute and long term settings.We will explore the types of delirium and quickly review mechanisms at the biopsychosocial levels and the evidence to support their contributions.We will also discuss possible treatment options and possibly provide prevention tools for the development of future deliriums.We will also examine risk factors associated with delirium and help clinicians in the early detection and treatment of delirium.