Biomimetic Synthesis of Basiliolides

来源 :The 24th International Society of Heterocyclic Chemistry Con | 被引量 : 0次 | 上传用户:cxsxj
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A biomimetic synthesis of the basiliolides, potent reversible inhibitors of sacroendoplasmic reticulum Ca2+-ATPase,[1] has been developed.The synthesis involved a 2-pyrone Diels-Alder cycloaddition for construction of the core of transtaganolide E and F,[2] which would be converted to the basiliolides via an O-acylation cyclization.
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院士简介:涂名旌(1928-),中国工程院院士,博士生导师,重庆文理学院兼职教授,重庆文理学院名誉院长,全国高等学校先进科技工作者。主要成果:获国家科技进步二等奖1项、三等奖1
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