【摘 要】
：
Objective: To investigates the meaning of these genes expression character and thephysiological significance of HIF-1α and HIF-1α for microtus oeconomus to survive at highaltitude environment.Methods:
【机 构】
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Research Center for High Altitude Medicine, Medical College of QinghaiUniversity
【出 处】
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中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议
论文部分内容阅读
Objective: To investigates the meaning of these genes expression character and thephysiological significance of HIF-1α and HIF-1α for microtus oeconomus to survive at highaltitude environment.Methods: This study was divided into three groups, there were highaltitude microtus oeconomus group (Qinghai, at an altitude of 4000 m), high altitudemouse group (at a simulated altitude of 4000 m for 30 days) and low altitude mouse group(Nanjing, at an altitude of 10 m), with 20 in each group, the tissues from liver, lung, kidneyand cardiac muscle were extracted respectively, the mRNA expression levels of HIF-1α andHIF-2α for different tissues were detected by real-time PCR method.
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