BMP4在耐药食管癌上皮-间质转化中的作用机制

来源 :2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 | 被引量 : 0次 | 上传用户：meganleejin

【摘要】

：

目的：食管癌(Esophageal carcinoma,EC)是消化道发病率最高的恶性肿瘤,易扩散转移,我国的食管癌发病率在肿瘤中高居第四。肿瘤多药耐药严重影响化疗效果,甚至导致化疗失败。因此,阐明食管癌转移及化疗耐受的分子机制,筛选鉴定相关标志物,对其进行靶向干预逆转,对提高食管癌治疗效果具有重要的理论价值和应用前景。

【作者】

：

周凯瑞石晓丽霍金玲杨腾蛟王淙

【机构】

：

郑州大学药学院,河南郑州,45000

【出处】

：

2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会

【发表日期】

：

2016年10期

【关键词】

：

BMP4 食管癌耐药 EMT

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