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Purpose: To investigate the effects of 10%hydrochloric acid solution(HCl)on conductivity,temperature,and coagulation in radiofrequency ablation(RFA).Materials and Methods: A monopolar Cool-tip RFA system was used to produce coagulation in ex vivo bovine liver.The study was classified into three groups: RFA-alone group,NaCl-RFA group(injection of 38.5%sodium chloride solution before RFA),and HCl-RFA group(injection of 10%hydrochloric acid solution before RFA).