【摘 要】
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Introduction & Objectives: Asian population has been reported to have lower incidence of prostate cancer,compared with other ethnic groups.Genetic polymorphism is hypothesized to be reason of variatio
【机 构】
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复旦大学附属肿瘤医院泌尿外科;复旦大学上海医学院肿瘤学系 复旦大学上海医学院肿瘤学系;复旦大学附属
【出 处】
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2012上海市医学会泌尿外科、男科学术年会
论文部分内容阅读
Introduction & Objectives: Asian population has been reported to have lower incidence of prostate cancer,compared with other ethnic groups.Genetic polymorphism is hypothesized to be reason of variation in prostate cancer incidence among different racial group.Published data on the association of prostate cancer susceptibility with polymorphisms in genes encoding Glutathione S-transferases(GSTs),which inactivate procarcinogens and thus contribute to carcinogenesis,are inconclusive.To more precisely address the role of GSTs polymorphisms(especially,GSTT1 and GSTM1 deletions)on prostate cancer risk in Asian descent,a meta-analysis was performed.
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