PTX3 AS A PARADIGM FOR THE INTERPLAY BETWEEN CELLULAR AND HUMORAL INNATE IMMUNITY IN INFLAMMATION AN

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：njsnw

【摘要】

：

Innate immunity consists of a cellular and a humoral arm.The long pentraxin PTX3 as originally cloned (cDNA and genomics, mouse and human) as an IL-1 inducible gene.

【作者】

：

Alberto Mantovani

【机构】

：

Istituto Clinico Humanitas,Humanitas University,Via Manzoni 56,20089 Rozzano,Italy

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Innate immunity consists of a cellular and a humoral arm.The long pentraxin PTX3 as originally cloned (cDNA and genomics, mouse and human) as an IL-1 inducible gene.

其他文献

The NEDD8-activating enzyme inhibitor MLN4924 induces G2 arrest and apoptosis of T-cell acute lympho

The first in class compound MLN4924 is a small molecule inhibitor that selectively inactivates NEDD8-activating enzyme (NAE).

会议

neddylationMLN492T-ALLG2 arrestapoptosisribosomal protein

Significance of CA125 combined with ratio of neutrophil to lymphocyte in the diagnosis and prognosis

Objective: To evaluate the sensitivity and specificity of CA125 combined with ratio of neutrophil to lymphocyte in the diagnosis and prognosis of ovarian cancer.The significance is to find a new marke

会议

Ovarian CancerTumor MarkersCA125Ratio of Neutrophil to Lymphocyte

Molecular Biomarkers of Pancreatic Intraepithelial Neoplasia and Their Implications in Early Diagnos

Lack of early detection and effective interventions is a major reason for the poor prognosis and dismal survival rates for pancreatic cancer.

会议

PanINsBiomarkerEarly DiagnosisTherapeutic Intervention

CXCR3+ B cells link interleukin-17 inflammation to protumorigenic macrophage polarization in human h

B cells consistently represent abundant cellular components in tumors;however, direct evidence supporting a role for B cells in the immunopathogenesis of human cancers is lacking, as is specific knowl

会议

B cellshepatocellular carcinomaIL-17

Function and mechanism of IL-36β on promoting antitumor immune response through activating CD8+T cel

Background: Cytokines play a pivotal role in breaking immune tolerance of tumor antigens and increase response rates to immunotherapy.

会议

interleukin-36βtumor microenvironmentCD8+T cellsmTORC1MyD88

Effectiveness and safety of cytokine-induced killer cells co-cultured with dendritic cells treatment

Objective: To evaluate efficacy and safety of dendritic cells in combination with cytokine-induced killer cell treatment of patients with colorectal cancer.

会议

Colorectal cancerDendritic cellsCytokine-Induced Killer cellsImmunotherapyCl

Activated Monocyte-Elicited Cancer Cell Autophagy Promotes Metastasis in Human Hepatocellular Carcin

Autophagy and tumor microenvironment have both been considered to be crucial for the tumor progression.However,little is known about the potential roles of microenvironment in the regulation and funct

会议

autophagyactivated monocytetumor metastasisHCC

UHRF1通过抑制TXNIP参与肾癌的恶性进展

背景：UHRF1(Ubiquitin-like protein containing PHD and RING finger domains 1)是一种多功能核蛋白，它在表观遗传学调控中发挥重要作用。

会议

UHRF1肾癌TXNIP表观遗传学表达调控

人源性抗前列腺特异性膜抗原单链抗体的表达、纯化及体内外活性鉴定

目的：将通过抗体噬菌体展示技术筛选获得的一株人源性抗前列腺特异性膜抗原(prostate specific membrane antigen,PSMA)的单链抗体,构建入原核表达载体,在大肠杆菌中诱导表达并纯化后,在体内外对其生物学活性进行鉴定。

会议

前列腺特异性膜抗原PSMA前列腺癌人源性单链抗体

The Compartmentalization of Immunological Memory: Bone Marrow is a Special Place

Recent evidence suggests that immunological memory does not only consist of memory lymphocytes circulating through the body, but that distinct and prominent populations of memory lymphocytes reside in

会议

PTX3 AS A PARADIGM FOR THE INTERPLAY BETWEEN CELLULAR AND HUMORAL INNATE IMMUNITY IN INFLAMMATION AN

与本文相关的学术论文