Explore Inhibition mechanism of potential inhibitors forThioredoxin Glutathione Reductase by Molecul

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：fxqq

【摘要】

：

【作者】

：

李家璜黄经纬华为建华子春

【机构】

：

南京大学医药生物技术国家重点实验室江苏教育学院生物系

【出处】

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中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

：

2014年3期

【关键词】

：

TGR Molecular docking Inhibition mechanism Schistosomiasis

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Schistosomiasis is the second most socioeconomically devastating parasitic disease, (aftermalaria) in the world.The current chemotherapy mainly relies on praziquantel.However, Schistosoma displaying low susceptibility to Praziquantel were found due to the massiveuse of this drug.It makes urgent to search therapeutic alternatives for schistosomiasistreatment.

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Explore Inhibition mechanism of potential inhibitors forThioredoxin Glutathione Reductase by Molecul

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