• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Topically delivered iPSs accelerate diabetic wound healing via heme oxygenase-1

Topically delivered iPSs accelerate diabetic wound healing via heme oxygenase-1

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：jinr0op3
【摘 要】
：
Poor blood and stem/progenitor cell supplies underlie wound healing impairment in diabetic patients.Induced pluripotent stem cells (iPSs) have great therapeutic potential;however,it is not clear wheth
【作 者】
：
Sifeng Chen Xinhong Wang Ming Xu Ning Li Meng Xiang Dan Meng Chao Lu Jing Quan Peng Lu Sun Ning Rui Wang Alex F. Chen 
【机 构】
：
Department of Physiology and Pathophysiology,Fudan University Shanghai Medical College,Shanghai,Chin
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
【发表日期】
：
2014年7期
【关键词】
：
iPSs diabetic wound healing heme oxygenase-1 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Poor blood and stem/progenitor cell supplies underlie wound healing impairment in diabetic patients.Induced pluripotent stem cells (iPSs) have great therapeutic potential;however,it is not clear whether iPSs can promote wound healing are unknown.Directly application of iPSs on a body or wound surface has not yet been reported.
其他文献
GSTpi protects against angiotensin Ⅱ-induced proliferation and migration of vascular smooth muscle c
Angiotensin Ⅱ (Ang Ⅱ)-elicited excessive proliferation,hypertrophy and migration of vascular smooth muscle cells (VSMCs) are vital to the pathogenesis of atheroclerosis.Glutathione S-transferase pi (G
会议
GSTpiAngiotensin ⅡVSMCSTAT3atherosclerosis
Oxidized high-density lipoprotein impairs endothelial progenitor cells function by activation of CD3
Aims:High density lipoprotein (HDL) levels inversely correlate with cardiovascular events due to the protective effects on the vascular wall and stem cells,which is susceptible to oxidative modificati
会议
Oxidized high-density lipoproteinendothelial progenitor cells
Nogo-B:an important regulator in the endoplasmic reticulum stress-mediated cardiac remodeling
Aims:Nogo-B plays crucial roles in vascular remodeling.However,its roles in cardiac remodeling remain unclear.The aim of this study was to investigate the function of Nogo-B in cardiac hypertrophy and
会议
Nogo-BCardiac hypertrophyEndoplasmic reticulum stress
自噬的下降是抗β1-肾上腺素受体自身抗体引起心肌细胞死亡的重要原因
心力衰竭已经成为影响人类健康和威胁生命的主要因素，而心肌细胞的反复丢失是心衰进程中最主要的因素之一。有研究证实抗β1-肾上腺素受体自身抗体(β1-AA)的存在可以引起成鼠心肌细胞死亡，并且认为凋亡是β1-AA 引起心肌细胞死亡的原因，然而单纯抑制凋亡并不能完全逆转β1-AA 所引起的心肌细胞的死亡。
会议
自噬β1-肾上腺素受体自身抗体
Gremlin Overexpression Enhances the Survival and Proangiogenic Function of Transplanted Mesenchymal
Rationale:Transplantation of culture-expanded mesenchymal stem cells (MSCs) often results in poor cellular engraftment,survival,and migration into sites of tissue injury.Gremlin (GREM),which different
会议
GremlinSurvivalProangiogenic FunctionMesenchymal Stem CellsIschemia
Nuclear-translocation of calreticulin aggravates endoplasmic reticulum stress-associated apoptosis d
Calreticulin (CRT) is a major Ca2+-binding chaperone mainly resident in the endoplasmic reticulum (ER) lumen.Recently,it has been shown that non-ER CRT regulates a wide array of cellular responses.We
会议
calreticulinhypoxia/reoxygenationendoplasmic reticulumCCAAT/enhancer-binding
S1P协同骨骼肌成肌细胞移植治疗大鼠急性心肌梗死的研究
目的 研究1-磷酸神经鞘氨醇(S1P)协同骨骼肌成肌细胞移植治疗急性心肌梗死的作用,为其临床应用打下基础。方法：结扎大鼠冠状动脉前降支建立急性心肌梗死模型,分别将无血清培养基、骨骼肌成肌细胞、导入S1P 的骨骼肌成肌细胞、导入脂质体的骨骼肌成肌细胞注射到梗死区,24 h 和48 h 后检测移植细胞的凋亡,4 周后检测心脏功能、心肌梗死面积变化,以阐明转基因骨骼肌成肌细胞对急性心肌梗死的治疗作用。
会议
S1P骨骼肌成肌细胞细胞移植急性心肌梗死凋亡
Chronic Vagus Never Stimulation (VNS) attenuates vascular endothelial impairment in ovariectomized r
Background and purpose:Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in postmenopausal women.And it has been known that is closely linked to the systemic inflammation.VNS
会议
Vagus Never StimulationCholinergic anti-inflammatory pathwayOvariectomyEndoth
AngiotensinⅡ-mediated autophagy regulates proliferation and migration of vascular smooth muscle cell
Autophagy is a highly conserved degradation process by which intracellular components,including soluble macromolecules and dysfunctional organelles are degraded by the lysosome.It plays an important r
会议
AngiotensinⅡautophagyVSMCsproliferationmigration
The Time Window Effect of Modified Yiyin Decoction on Endothelium-Dependent Vasodilation in Ovariect
The aim of present study was to investigate the time window effect of modified Yiyin Decoction on endothelium-dependent vasodilation in the one,three and six months after castration.The ovariectomied
会议
Modified Yiyin DecoctionTime Window EffectEndothelium-Dependent Vasodilatione