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5. Abnormal homeostasis of bivalent metals in Alzheimer's disease

Abnormal homeostasis of bivalent metals in Alzheimer's disease

来源 :2nd International Neural Regeneration Symposium(INRS2012)(第二 | 被引量 : 0次 | 上传用户：fsongyifa

【摘 要】

：

Accumulation of brain amyloid-β is a pathological feature of Alzheimers disease.Dyshomeostasis of bivalent metals such as zinc, iron and copper initiate amyloid-β deposition and the formation of senil

【作 者】

：

Zhanyou Wang 

【机 构】

：

Key Laboratory of Medical Cell Biology of Ministry of Education, China Medical University, Shenyang

【出 处】

：

2nd International Neural Regeneration Symposium(INRS2012)(第二

【发表日期】

：

2012年8期

【关键词】

：

Alzheimer's disease amyloid-β APP zinc transporter divalent metal transport 

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　　Accumulation of brain amyloid-β is a pathological feature of Alzheimers disease.Dyshomeostasis of bivalent metals such as zinc, iron and copper initiate amyloid-β deposition and the formation of senile plaques.

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