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目的 肺癌是全世界癌症相关死亡最常见的原因，其中超过85％的肺癌是非小细胞肺癌。据统计，高达69％的晚期非小细胞肺癌患者可能有一个潜在的可操作的分子靶点。临床上成纤维细胞生长因子受体1(FGFR1)和SOX2 高表达与非小细胞肺癌患者生存时间短呈正相关。
在FGFR1扩增型非小细胞肺癌中FGFR1通过SOX2调控PDL1表达的信号传导分子机制研究
【摘 要】
：
目的 肺癌是全世界癌症相关死亡最常见的原因，其中超过85％的肺癌是非小细胞肺癌。据统计，高达69％的晚期非小细胞肺癌患者可能有一个潜在的可操作的分子靶点。临床上成纤维细胞生长因子受体1(FGFR1)和SOX2 高表达与非小细胞肺癌患者生存时间短呈正相关。
【机 构】
：
上海交通大学MED-X研究院
【出 处】
：
2019中国肿瘤学大会
【发表日期】
：
2019年7期
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