TREM-2 function as a negative immuno-regulatory molecule through Syk pathway and partially predict p

来源 :2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户：zuochangfeng

【摘要】

：

【作者】

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Yinan Yao Hequan Li Junjun Chen Guohua Lu JianyingZhou

【机构】

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Department of Respiratory and Critical Care Medicine,First Affiliated Hospital of Zhejiang Universit

【出处】

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2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议

【发表日期】

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2014年3期

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Objective In the inflammatory setting, Triggering Receptor Expressed on Myeloid cells-2 (TREM-2) restrains phagocytosis of both dendritic cells (DCs) and macrophages (Mφs) as well as reduces their cytokines release through DAP12 signal.However, the role of TREM-2 signal in cancer bas never been elucidated.

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