【摘 要】
:
Existing cyclooxygenase-2 (COX-2) selective inhibitors, a form of non-steroidal anti-inflammatory drugs (NSAIDs) that selectively targets COX-2, significantly reduce the gastrointestinal adverse event
【机 构】
:
School of Chinese Medicine, Hong Kong Baptist University, Hong Kong Special Administrative Region, C
【出 处】
:
纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会
论文部分内容阅读
Existing cyclooxygenase-2 (COX-2) selective inhibitors, a form of non-steroidal anti-inflammatory drugs (NSAIDs) that selectively targets COX-2, significantly reduce the gastrointestinal adverse events, but may cause an increased cardiovascular risk.
其他文献
It is believed that circulating tumor cells carry important information of cancer progression and metastatic potential.However, the rarity of CTCs in peripheral blood makes it challenging to be detect
Smart nanoparticles (NPs) that respond to external stimulation, such as light, hyperthermia,and reduction/oxidation, have been developing to achieve optimal drug release in tumor tissues.
Recently, mesoporous silica nanoparticles (MSNs) have attracted increasing interest in biomedical applications, especially in controlled drug delivery system, owing to their unique advantages includin
Photodynamic therapy (PDT) is an extraordinary method to treat cancer which employs a photosensitizer (PS) molecule that absorbs light and produces reactive oxygen species (ROS),such as singlet oxygen
Photothermal therapy (PTT) of cancer has drawn great attention owing to its advantages such as minimal invasion, fewer complications and reduced side effects for normal tissues compared to conventiona
Stimuli-responsive polymeric micelles bearing segments drawn from biocompatible species have increased great attention as drug delivery for their biocompatibility, controlled drug release, enhanced th
Biodegradable drug delivery carder is valuable in the treatment of peripheral nerve injury.In this study, biodegradable material polylactic acid was chosen as matrix and brain-derived neurotrophic fac
As one of most widely used anticancer drugs, doxorubicin (DOX) still has limited clinical applications, due to its insufficient cellular uptake and existence of drug resistance.1 To overcome these pro
Nowadays, much effort has been devoted to the research of more efficient cancer therapies.Nanotechnology approaches are currently the most promising methods [1,2].Heat treatment is one of the most stu
Novel tumor-targeting hyaluronidase activatable nanoparticles have been prepared by covalentattachment of hydrophobic chlorin e6 to hyaluronic acid (HA).DOX encapsulating the nanoparticles(HA-Ce6) sho