Local administration of microtubule-targeting agent promote motor functional recovery after spinal c

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：kiry250

【摘要】

：

Spinal cord injury (SCI) is a devastating traumatic event which can lead to a range of health problems beyond sensory and motor dysfunction.Moderate microtubule stability with low dose of Taxol(R) or

【作者】

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Xiaoling Li Yuelong Wang Liangxue Zhou Gang Guo

【机构】

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State Key Laboratory of Biotherapy and Cancer Center,and Department of Neurosurgery,West China Hospi

【出处】

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Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

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2016年11期

【关键词】

：

spinal cord injury axonal regeneration docetaxel drug delivery

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　　Spinal cord injury (SCI) is a devastating traumatic event which can lead to a range of health problems beyond sensory and motor dysfunction.Moderate microtubule stability with low dose of Taxol(R) or epothilone B could reduce axon-inhibitory scarring while boost intrinsic axonal growth,and ultimately improve sensorimotor function after rodent SCI[1].

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Local administration of microtubule-targeting agent promote motor functional recovery after spinal c

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