PKA通过Hippo信号通路抑制甲状腺乳头状癌进展

来源 :2019中国肿瘤学大会 | 被引量 : 0次 | 上传用户:pxz521520
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  目的 甲状腺癌(thyroid carcinoma,TC)是最常见的内分泌恶性肿瘤。蛋白激酶A(protein kinase A,PKA)参与多种细胞的生物学调控。环化腺核苷一磷酸(Cyclic Adenosine monophosphate,cAMP)在真核生物中的主要功能是激活cAMP 依赖性蛋白激酶(PKA)。
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