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The genus Pholidota(Orchidaceae)belongs to the tribe Coelogyneae,and comprises ca.30 species with a distribution from tropical Asia to tropical Australia.Among them,ca.14 species occur in China[1].Pholidota Cantonensis Rolfe.,named ‘Xi-Ye-Shi-Xian-Tao’ in Chinese,is a Chinese folk herbal medicine,with a long history of safe use for treating sore throat,tonsillitis,cough phlegm asthma,pneumonia,acute soft tissue trauma and arthritis[2,3].Previous phytochemical study on P.cantonensis showed the existence of stibenoids,cycloartane triterpenoid and phenylpropanoids[4,5].Based on the previous study the 80%ethanol extract of the whole plant P.cantonensis was separated by chromatography on silica gel,Sephadex LH-20,MCI gel and afford 22 compounds,the structures of compounds were elucidated on the basis of the chemical evidence and 1H-NMR,13C-NMR,2D-NMR and MS spectral.Four new constituents were isolated by the column chromatography over silica gel,MCI gel,RP-18 silica gel,Sephadex LH-20 and pre-HPLC from the EtOH extract of the air-dried whole plant of Pholidota cantonensis Rolfe.,together with 18 known compounds.The structures of the new compounds were established as 1-hydroxy-2,7-dimethoxy-9,10-dihydrophenanthrene-[4,5-bcd] furan(1),5-hydroxy-2,7-dimethoxy-9,10-dihydro-1,4-Phenanthrenedione(2),ent-labd-13(E)-ene-3α,8β,15-tri-3-O-β-D-glucopyranoside(3),5α,10β-ent-cleroda-3,13(E)-diene-15,18-diol-15-O-β-D-glucopyrannoside-18-O-β-Dglucopyrannoside(4)by chemical and spectroscopic methods,including 1D and 2D NMR.