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Boron nitride nanosheet and copper sulfide nanocomposites(BNNS@CuS)were prepared,and they display an intrinsic catalytic activity towards conventional substrate 3,3,5,5-tetramethylbenzidine(TMB)in the presence of H2O2.The catalytical oxidation induces colour variation.Their intrinsic peroxidase-like activity is dependent upon temperature,pH and H2O2 concentration.