Several studies about the relationship between depression and chronic non malignant pain have been made.These studies have shown that up to 50% of chronic pain patients are depressed.It is reasonable to expect that pain patients would have an increased risk of suicidal behaviour.This study is part of two studies from The Pain Clinic, Odense University Hospital; The study has the following purposes: Based on the data recorded in patients consecutively referred to the Pain Clinic, OUH for the period 1.9 2008 to 31.12 2009, patients with suicidal behaviour are compared to patients without suicidal behaviour to identify risk factors for suicidal behaviour in pain suffering patients.Material The Pain Clinic, OUH receives patients with chronic pain from the entire region of Southern Denmark.In the study period data on the following issues for all patients have been registered.Pain History Symptom Duration Social Characteristics, Alcohol Consumption Medication Consumption the following scales have been used: Brief Pain Inventory Disability Rating Index VAS Scale for assessment of pain SF-36 short version The following questions are asked about suicidal behaviour: Have you ever tried to take an overdose of medication or otherwise harm yourself? Did your action have any relation to your pain condition? Did you have any contact with health professionals after your self harm? Patients with suicidal behaviour are compared to patients without suicidal behaviour.Results: In the study period 701 patients, 237 men and 464 women have been treated in the Pain Clinic.Ninety patients (12.8%) had previously made a suicide attempt, 48 of these patients (54%) stated that their suicide attempt had relation to their pain condition.Fifty two (58%) patients had had contact with a health professional in relation to their suicide attempt.No difference between suicidal and not suicidal patients was seen as regards sex, age, use of medication and daily activities.Significant differences were seen between the two groups as regards: Abuse of alcohol, tobacco smoking, and pain duration, early debut of pain, VAS score and problems to sleep.On the SF 36 statistically significant differences between the two groups are found in the areas of physical limitations (RP), bodily pain (BP), psychological constraints (RE) and mental health (MH).Conclusion: 12.8% of patients with chronic pain reported having made a suicide attempt, and more than 1/2 of the suicide attempt were related to their pain condition.Patients with a history of suicide attempts differed from patients without suicide attempts in areas relating to the pain condition including long-duration, early onset, greater pain intensity, sleep problems and abuse problems.Assessed by SF36 these problem areas in patients with a history of suicide attempts were confirmed, and also mental constraints and poor psychological well-being were significant risk factors for suicide attempts in chronic pain patients.The results are preliminary and are based solely on univariate analysis.They show however a very clear risk of the vulnerability of chronic pain patient with suicide attempts.